procedure TForm1.FormCreate(Sender: TObject);
var
  i, j: integer;
  s: string;
  c: set of char;
begin
  c := ['А'..'Я', 'а'..'я'];
  memo1.Lines.LoadFromFile('c:\11.txt');
  for i:=0 to memo1.Lines.Count do
  begin
    s:=memo1.Lines.Strings[i];
    for j:=1 to length(s) do
      if chr(ord(S[j])+64) in c then
        s[j]:=chr(ord(S[j])+64);
    memo1.Lines.Strings[i]:=s;
  end;
end;